に定義されています 急速進行性糸球体腎炎

Rapidly Progressing Glomerulonephritis (RPGN, also known as Crescentic Glomerulonephritis) is a form of acute Glomerulonephritis that results in severe injury to kidney glomerulus. よりたくさんの

Rapidly Progressing Glomerulonephritis (RPGN, also known as Crescentic Glomerulonephritis) is a form of acute Glomerulonephritis that results in severe injury to kidney glomerulus. The damage inflicted causes leakage of plasma proteins into the glomerulus which stimulate parietal epithelial cells lining Bowman's space along with infiltrating monocytes to form a crescent-shaped scar. As more and more glomeruli become disfunctional due to scarring, other glomeruli become larger (hypertrophy) to pick up the slack and maintain the glomerular filtration rate. This stresses the remaining glomeruli, causing them to become damaged, leading to a downwards spiral into acute renal failure. less