pleasant

低筋緊張, 心雑音, 発達の遅れ, 顔変形

Down syndrome or trisomy 21 (also Down's syndrome) is a genetic disorder caused by the presence of all or part of an extra 21st chromosome. It is named after John Langdon Down, the British doctor who first described it in 1866. 

増加関節の動き, 明るい性格, 顔変形

Cohen syndrome has several characteristics such as obesity, mental retardation and craniofacial dysmorphism. It has an autosomal recessive transmission with variable expression. ... 

は体重が増え, 明るい性格, 発達の遅れ

異常歩行, 発達の遅れ, 貧しい人々の社会的スキル, 高血圧

Williams syndrome (also Williams-Beuren syndrome, sometimes called Pixieism) is a rare genetic disorder, occurring in fewer than 1 in 7,500 live births.It is characterized by a distinctive, "elvish" facial appearance, along with a low nasal bridge; an unusually cheerful demeanor and ease with strangers, coupled with unpredictably occurring negative outbursts; mental retardation coupled with unusual (for persons who are diagnosed as mentally retarded) language skills; a love for music; and cardiovascular problems, such as supravalvular aortic stenosis and transient hypercalcaemia.